Clinical research is a branch of healthcare science that determines the safety and effectiveness (efficacy) of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatment, diagnosis or for relieving symptoms of a disease.

Translational research includes two areas of translation. One is the process of applying discoveries generated during research in the laboratory, and in preclinical studies, to the development of trials and studies in humans. The second area of translation concerns research aimed at enhancing the adoption of best practices in the community. Cost-effectiveness of prevention and treatment strategies is also an important part of translational science.

Department of Emergency Medicine

Program Overview:

The Department of Emergency Medicine is currently investigating innovative and novel approaches to increase early stage medical student participation in clinical research that will enrich and further develop their skills in research methodology, scientific inquiry, and application of evidence based medicine. Such skills are required for high impact medical practice in today’s ever-changing health care environment as well as in the arena of scientific and medical discovery. The purpose of this program is to provide a structured environment that engages and cultivates medical students’ interest, experience, and training in performing clinical research specific to emergency medicine. The long-term goals of the program are to develop a strong foundation to pursue research endeavors upon graduating and foster an interest in emergency medicine.

Research:

Trainees will engage in a mentored emergency medicine clinical research experience. The program is designed to: 1) increase student awareness in the value of doing clinical research; and 2) strongly support students interested in academic emergency medicine. Trainees will have the opportunity to work in a busy, high-volume emergency department (ED) either at IUH Methodist, IUH Riley Hospital for Children, and/or Eskenazi Health Hospital. The data collected by the participants are analyzed and interpreted in conjunction with their research mentor on a wide variety of ongoing studies and continuous quality improvement projects.

Activities:

In addition to hands-on clinical research experience, program participants will be actively involved in a weekly data/journal club as well as research training in the principles of study enrollment, informed consent, study design, data management, and various other research methodologies.

Eligibility:

Medical students in good standing who will have completed their first year (M1) by the summer program onset are eligible to apply. Each accepted student will be paired with a highly qualified faculty mentor for the 10-week summer research program.

The program is only available in the Indianapolis area. Applicants must be willing to work rotating shifts (including overnight shifts) in the clinical environment. Weekend shifts will be expected. Emergency Departments operate 24/7, so there will be opportunities every day to engage in research and experiential learning.

Outcomes:

At the end of the 10 weeks, each participant will submit an abstract to and present a poster at an IUSM IMPRS Poster Session on July 29, 2018. It is also likely that the culmination of the research project will be included in a manuscript and/or presentation at a national meeting and that the student will have co-authorship on the published work.

Application Process:

Applications are due on January 29, 2018. To apply for the Department of Emergency Medicine program, fill out the RedCap application form. You will be able to save and return to your application until you are ready to submit for review.

Contact Information:

For additional information about the program, please contact Lane Coffee at rlcoffee@iu.edu or imprs@iupui.edu.

Department of Surgery Summer Research Opportunity

Program Overview:

The IU School of Medicine Department of Surgery offers up to six summer research opportunities for first year medical students. Research opportunities are available in the areas of surgery basic science and translational/clinical topics. First-year medical students who are interested in the program are encouraged to identify potential mentors within the department and to develop a short, 300-word research proposal to be reviewed by program leadership. Proposal submissions are due no later than April 15.

Proposals will be reviewed and the most meritorious applications funded. Students will receive a $2,500 stipend for the eight weeks of research. Students should expect to begin working full time between after May 19 and continue for eight weeks. Mentors of the program include Brian Brewer, MD; Leonidas Koniaris, MD; Milan Radovich, PhD; Bruce Robb, MD; and Teresa Zimmers, PhD.

Application Process:

To apply for the Department of Surgery Summer Research Opportunity, fill out the RedCap application form for submission. The form will allow you to save and return to your application until you are ready to submit for review.

Faculty Mentors:

Please go to https://medicine.iu.edu/departments/surgery/faculty for the list of faculty.

Contact Information:

If you have questions about the Department of Surgery Summer Research, please email Dr. Leonidas Koniaris at lkoniari@iu.edu.

Division of Gastroenterology and Hepatology

Program Overview:

As a part of the Indiana Medical Student Program for Research and Scholarship (IMPRS), the Division of Gastroenterology/Hepatology is delighted to offer up to ten 2018 summer research opportunities for Indiana University School of Medicine medical students completing their first year of training (MS1). Our division, one of the largest in the country, firmly believes in the early promotion of clinical and translational research exposure among medical trainees. This first step in the development of a working scientific skillset is applicable in any future medical career and is a critical instrument for the next generation physician. Execution of the IMPRS program within the Division of Gastroenterology/Hepatology will provide a structured ten-week summer experience aimed to develop basic research skills and knowledge within clinical and translational investigation focused in gastroenterology or hepatology. The long-term goal of this program is to increase medical student exposure and experience to research methods, foster scientific intrigue, and nurture hypothesis-driven investigation beyond the traditional medical education program.

Research:

Students will be paired with highly selected and experienced research mentors, all with active research programs in the Division of Gastroenterology and Hepatology. Our faculty has an extensive track record in research productivity, as evident by more than 150 publications in the year 2016 alone. Research projects will be individually developed to overlap the research mentor expertise as well as the student’s scientific interest, prior experience, and future career goals. Resultant project data will be compiled, analyzed, and interpreted in conjunction with the research mentor. In addition to project activity, each student will attend a series of weekly seminars and participate in the poster session at the end of the summer session on July 27, 2018. The research poster session will allow the student an opportunity to present their project background, aims, methods, results, and conclusions. The posters will be judged and twenty projects will be selected to compete for awards in the oral presentation on August 1, 2018.

Eligibility:

IUSM medical students (M1) who will have completed their first year by the summer program onset are eligible to apply. This program will only be available to students within the Indianapolis area.

Outcome of Research Projects:

IMPRS participants within the Division of Gastroenterology/Hepatology will be expected to submit a research abstract and participate in the poster session at the end of the summer session. Further, it should be expected that the research contribution of the trainee to be included in a submitted manuscript or presented at a national gastroenterology or hepatology meeting. The research student will have co-authorship on any published work arising from the research program.

Faculty Research Mentors:

Hepatology (2-3 positions):

Mentors: Drs. Chalasani, Liangpunsakul, Vuppalanchi, Ghabril, Gawrieh, Liang, Orman, & Lammert

Our hepatology faculty represent a spectrum of thought leaders and internationally known physicians with highly active clinical-research careers. We can support research within a diverse realm of liver diseases in both pre- and post-transplant patients. Available mentors are supported by a number of federal grant mechanisms, supporting investigation dedicated to alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), HIV in NAFLD, inpatient liver-related outcomes, and autoimmune hepatitis. Beyond these dedicated grants, we have robust, ongoing investigator-initiated clinical research within noninvasive assessment of liver fibrosis, autoimmune liver disease, drug-induced liver injury, and even applications within social media. A lab-based hepatology experience is also available with Dr. Liang, an experienced scientist with expertise in molecular biology and genetics. Beyond working with the research mentor, the paired students within the hepatology tract will also work closely with the hepatology research team and participate in weekly Monday research meetings.

Gastroenterology (7-8 positions):

Inflammatory Bowel Disease and Clostridium Difficile Infection:
Mentor: Dr. Fischer

Dr. Fischer is a national leader in inflammatory bowel disease (IBD) and spearheads the IBD program at IU. She is recognized for her work with the IBD clinical trials program and the development of the fecal microbial transplantation program for the treatment of clostridium difficile infection among other conditions.

Neurogastroenteroloy and Motility:

Mentors: Drs. Wo, Nowak, & Shin

Drs. Wo and Nowak lead the IU motility group and have far reaching recognition for their expertise and contributions in gut dysmotility and associated disorders. Alongside leaders at Purdue University, Dr. Nowak is also a coinvestigator with a NIH innovation grant examining therapeutics in the realm of electroceuticals for gut dysmotility. Dr. Shin is promising clinician scientist and her research focus is on the effects of bile acids and microbiome in irritable bowel syndrome.

Medical Informatics in Gastroenterology:

Mentor: Dr. Imler

Dr. Imler is a gastroenterologist but also the Director of the Data Core for the Regenstrief Institute. This world renowned center, key in many high impact publications, is a central resource for electronic healthcare data access for both the Regenstrief Institute and IU. Dr. Imler has extensive experience in the implementation of medical informatics (application of the Data Core) in clinical investigation focused in gastroenterology.

Endoscopic:

Mentor: Dr. Rex

Beyond being the active Chief of GI Endoscopy at IU, he is a master clinician and an internationally known gastroenterologist with an extensive track in record in education, endoscopic tool development, and research within multiple aspects of colonoscopy.

Advanced Endoscopy:

Mentors: Drs. Sherman & Fogel

The advanced endoscopy faculty at IU are internationally recognized authorities (icons) in therapeutic ERCP and EUS for a multitude of pancreaticobiliary conditions. The group is well-represented in many facets of scientific investigation that include all aspects of ERCP and EUS and new endoscopic device and technology. Further, Dr. Fogel is a part of the Consortium to Study Chronic Pancreatitis, Diabetes, and Pancreatic Cancer Clinical Centers (CPDPC). The CPDPC is a large, federally funded multi-collaborator grant tasked with elucidating the relationship between chronic pancreatitis, pancreatogenic diabetes, and pancreatic adenocarcinoma.

Application:

Applications are due on January 29, 2018. To apply for the Division of Gastroenterology and Hepatology program, fill out the RedCap application form. You will be able to save and return to your application until you are ready to submit for review.

Contact Information:

Questions about the Faculty or possible projects/research experiences should be directed to Craig Lammert, MD by email.

Cancer in Under Privileged, Indigent or Disadvantaged (CUPID) Summer Translational Research Program

Program Overview:

The Cancer in Under Privileged, Indigent or Disadvantaged (CUPID) Summer Translational Research Program is an NCI-funded, bi-institutional oncology fellowship with a focus on laboratory-based research. The program provides an intensive, structured, laboratory-based research experience.

Frequently Asked Questions:

Read the frequently asked questions.

Application Process:

Registration for the 2018 summer program will be announced in December, 2017. Students interested in applying for CUPID should first complete an online registration. The application itself includes a written personal statement (500 words or less), a personal photograph, two recommendation letters, and a Curriculum Vitae (CV) or resume. Upon completing the initial registration, students will be given a link to send to their referees to upload their recommendation letters. For more information, please refer to CUPID’s webpage.

Contact Information:

Refer to this webpage for a listing of program contact information.

Student Research Fellowship Program (SRFP) at IUSM-Fort Wayne

Program Overview:

The Student Research Fellowship is a structured program developed to provide students with basic research skills and practical experience in conducting research independently. Registration and detailed information about the 2018 summer program will be announced in December 2017.

Student Eligibility:

First-and second-year students enrolled in an accredited program (DO or MD) are eligible to apply to this program. These students will be expected to lead the student research team and should expect to spend approximately 40 hours per week committed to the research project for 10 weeks.

Application Process:

To apply for Student Research Fellowship Program, applicants must complete and submit the SRFP application by 5 pm on January 31, 2018. Two (2) letters of recommendation are required. One letter must be from a faculty member at the school in which the applicant is attending. The application form and each letter of recommendation must be submitted directly to Gina Bailey. For more details about the Student Research Fellowship Program, call the IUSM-Fort Wayne office at 260-481-6730 or Gina Bailey, IU School of Medicine, at 260-481-6731. Students will be notified of acceptance into the program by February 28, 2018.

Contact Information:

For additional information about the Student Research Fellowship Program, please contact Gina Bailey from IU School of Medicine in Fort Wayne by baileyg@ipfw.edu.

Hospital Medical Education Program (HME)

Program Overview:

We would like to invite you to participate in the 2018 HME Program. The Indiana State Medical Association and the Indiana Hospital Association endorse this program, in conjunction with the participating Indiana hospitals. download the complete list of the participating hospitals for 2018.

This unique program offers Indiana first-year medical students the opportunity to spend a portion of their 2018 summer in one of the participating community hospitals within the state of Indiana learning about clinical medicine and community health. Participating hospitals may or may not pay students a nominal stipend (with a few having limited additional offerings). Depending on the individual hospitals, the summer experiences typically runs from four to eight weeks spending at least 40 hours/week in the hospital. Students may not hold other jobs concurrently that would be in direct conflict with the hospital obligations.

Application Process:

Be mindful that some hospitals require an interview (check the participating hospital contact on the interview requirements). If the hospital you are interested in requires an interview, you must contact the hospital directly either by phone or email provided to schedule the interview. Hospitals requiring an interview may conduct the interview in person, by phone or by some other means. Applicants must complete the required interview by no later than Friday, February 2, 2018. This is the same due date for the HME Program Application form (whereby you will indicate your hospital preference(s). Participating Hospitals that require an interview require that the applicant submit the HME Student Application prior to the interview. This will allow the participating hospital to have the application prior to the interview.

The HME Program Application is due no later than February 2, 2018. You may fax it to (317) 278-2691. The preferred method is to receive the application as an attachment to an email. Please complete the application, save it as a PDF document to your computer and send it as an attachment via email. It is a fillable PDF application for your convenience.

If demand exceeds supply (which will be the case inevitably), priority is given to the applicants ranked by the participating hospitals; otherwise, assignments will be made according to geographical availability and expressed interest. Hospital assignment will be completed by February 16, 2018 and the selected applicant notified by email soon thereafter.

The Indiana University School of Medicine may ask participating students to write an abstract describing an instructive clinical case or scenario they observed, and to provide the completed abstract to their Lead Academic Advisor in order document formally their participation in the HME program. While the sponsoring medical staff are not obligated to assist in the preparation of this abstract, we have notified participating hospitals that IUSM students may request permission, advice or insight for this assignment.

Forms and Documents:

Contact Information:

Should you have any questions concerning the HME Program, please do not hesitate to contact Jose Espada at (317) 274-1967 or via email.

Emergency Room Experiential Opportunity at IUSM-West Lafayette

Program Overview:

The Emergency Room Experiential Opportunity is an 8-week program to provide the students an opportunity in the Physician shadowing program in the Emergency Medicine Department of Greater Lafayette hospitals. The number of opportunites for 2018 has not yet been determined.

Student Eligibility:

Only first year IUSM-West Lafayette students are eligible to apply to this program. West Lafayette campus students are provided application materials in November with a due date of January 12, 2018.

Contact Information:

For additional information, please contact Dr. Ray Munguia at rmunguia@purdue.edu.